SCHEMBL21471673

SCHEMBL21471673

C=CCN1CCc2cc(C(O)C(C)Nc3ccccc3C)sc2-c2ccc(F)cc21

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PER2 O15055 1/20 0.30
CRY2 Q49AN0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21471795 0.76 IDO1 (0.33)
SCHEMBL21471672 0.73 CTSS (0.34) PER2CRY2
SCHEMBL21458042 0.72 CHRM2 (0.35) PER2CRY2
SCHEMBL21471675 0.71 ALDH1A1 (0.47)
SCHEMBL21471792 0.71 CHRM2 (0.36) PER2CRY2
SCHEMBL21471717 0.70 MAPK14 (0.41)
SCHEMBL21474620 0.70 MAPK14 (0.41)
SCHEMBL20599068 0.70 NOTUM (0.46)
SCHEMBL21471714 0.70 CHRM2 (0.38)
SCHEMBL20619490 0.70 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019199908-A1 HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2019-10-17 WO disclosed