SCHEMBL21472987

SCHEMBL21472987

c1ccc(-c2cccc3c4ccc5c6ccccc6c6cccc7c6c5c4n7c23)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 2/20 0.35
CCND1 P24385 2/20 0.35
MAPK14 Q16539 1/20 0.35
HSD17B10 Q99714 2/20 0.34
HTR6 P50406 2/20 0.34
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
PLEC Q15149 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.32
MAP4K4 O95819 1/20 0.32
CSF1R P07333 1/20 0.32
FGFR1 P11362 1/20 0.32
PDGFRA P16234 1/20 0.32
LTK P29376 1/20 0.32
KDR P35968 1/20 0.32
MAPK8 P45983 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21461880 0.97 MAPK14 (0.34) CDK4CCND1MAPK14HSD17B10HTR6
SCHEMBL21472988 0.91 PRKDC (0.33) CDK4CCND1MAPK14HSD17B10KDM4E
SCHEMBL21473101 0.90 MEN1 (0.34) CDK4CCND1MAPK14HSD17B10KDM4E
SCHEMBL21472969 0.88 ALDH1A1 (0.31) HSD17B10DUSP3HPGDALDH1A1
SCHEMBL21472971 0.87
SCHEMBL21473094 0.86 TNF (0.42) HTR6CYP1A2
SCHEMBL21472972 0.86 MEN1 (0.40) KDM4EMEN1MAPTKMT2ATDP1
SCHEMBL21473093 0.86 TNF (0.42) HTR6CYP1A2
SCHEMBL21473092 0.86 TSHR (0.35) HSD17B10KDM4EMEN1MAPTKMT2A
SCHEMBL21473044 0.85 HSD17B10 (0.35) CDK4CCND1MAPK14HSD17B10HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 CDK4 4092/4885CCND1 1500/4885MAPK14 4072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.