SCHEMBL21472988

SCHEMBL21472988

c1ccc(-c2cccc(-c3cccc4c5ccc6c7ccccc7c7cccc8c7c6c5n8c34)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.33
PTGER1 P34995 1/20 0.33
PTGER4 P35408 1/20 0.33
PTGER3 P43115 1/20 0.33
PTGER2 P43116 1/20 0.33
HSD17B10 Q99714 1/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
PLEC Q15149 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CAMK2D Q13557 1/20 0.31
MAOB P27338 1/20 0.30
MAPK14 Q16539 1/20 0.30
CDK4 P11802 1/20 0.30
CCND1 P24385 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21472971 0.93
SCHEMBL21461880 0.91 MAPK14 (0.34) HSD17B10KDM4EMEN1MAPTRECQL
SCHEMBL21472987 0.91 CDK4 (0.35) HSD17B10HPGDKDM4EMEN1MAPT
SCHEMBL21473045 0.89 KDM4E (0.32) PRKDCPTGER1PTGER4PTGER3PTGER2
SCHEMBL21472969 0.88 ALDH1A1 (0.31) HSD17B10HPGD
SCHEMBL21472974 0.83 GSTP1 (0.38) PRKDCHSD17B10HPGD
SCHEMBL21473101 0.82 MEN1 (0.34) HSD17B10HPGDKDM4EMEN1MAPT
SCHEMBL21472952 0.82 KDM4E (0.32) HPGDKDM4EMEN1MAPTRECQL
SCHEMBL21472962 0.82 POLB (0.31) HPGDKDM4EMEN1MAPTKMT2A
SCHEMBL21472981 0.81 TSPO (0.38) HSD17B10HPGDKDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 PRKDC 4315/4885PTGER1 2195/4885PTGER4 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.