SCHEMBL21473042

SCHEMBL21473042

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccc6c7ccccc7c7cccc8c7c6c4n58)ccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
PTGER4 P35408 1/20 0.33
TSPO P30536 1/20 0.32
HDAC4 P56524 1/20 0.32
KMT2A Q03164 3/20 0.32
IL1R1 P14778 1/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
MAPK1 P28482 1/20 0.31
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21473103 0.95 KDM4E (0.39) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL24703225 0.91 KDM4E (0.47) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL21473077 0.90 KDM4E (0.34) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL21454096 0.89 KDM4E (0.55) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL21473029 0.89 KDM4E (0.43) L3MBTL1KDM4EATMPTGER4HDAC4
SCHEMBL21473048 0.89 KDM4E (0.43) L3MBTL1KDM4EATMPTGER4HDAC4
SCHEMBL21473926 0.89 KDM4E (0.45) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL20444349 0.89 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL21454263 0.88 KDM4E (0.40) L3MBTL1KDM4EATMPTGER4HSD17B10
SCHEMBL24703228 0.88 KDM4E (0.42) L3MBTL1KDM4EATMPTGER4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 L3MBTL1 1153/4885KDM4E 4292/4885ATM 4281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.