SCHEMBL21473048

SCHEMBL21473048

c1ccc(-n2c3ccccc3c3cc(-c4cccc5c6ccc7c8ccccc8c8cccc9c8c7c6n9c45)ccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
DUSP3 P51452 1/20 0.32
PTGER4 P35408 1/20 0.32
HDAC4 P56524 1/20 0.31
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26285946 0.92 L3MBTL1 (0.44) KDM4EATML3MBTL1DUSP3PTGER4
SCHEMBL26284039 0.91 L3MBTL1 (0.46) KDM4EATML3MBTL1DUSP3PTGER4
SCHEMBL26285977 0.91 KDM4E (0.43) KDM4EATML3MBTL1DUSP3PTGER4
SCHEMBL26285979 0.91 KDM4E (0.43) KDM4EATML3MBTL1DUSP3PTGER4
SCHEMBL21472959 0.90 L3MBTL1 (0.45) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL26285947 0.89 KDM4E (0.42) KDM4EATML3MBTL1DUSP3PTGER4
SCHEMBL26284032 0.89 KDM4E (0.44) KDM4EATML3MBTL1DUSP3PTGER4
SCHEMBL21473042 0.89 L3MBTL1 (0.46) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL26286001 0.89 KDM4E (0.39) KDM4EATML3MBTL1DUSP3PTGER4
SCHEMBL26285959 0.88 KDM4E (0.47) KDM4EATML3MBTL1DUSP3PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 KDM4E 4292/4885ATM 4281/4885L3MBTL1 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.