SCHEMBL21473099

SCHEMBL21473099

c1cc(-c2ccc3c4ccccc4c4ccc5c6ccccc6n6c2c3c4c56)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
DUSP3 P51452 1/20 0.32
KMT2A Q03164 2/20 0.30
POLB P06746 2/20 0.30
IL1R1 P14778 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21472959 0.87 L3MBTL1 (0.45) KDM4EATML3MBTL1KMT2APOLB
SCHEMBL21473045 0.85 KDM4E (0.32) KDM4EKMT2APOLBMEN1ALDH1A1
SCHEMBL21472962 0.84 POLB (0.31) KDM4EKMT2APOLBMEN1ALDH1A1
SCHEMBL21472958 0.83 HSP90AA1 (0.33) KDM4EKMT2APOLBMEN1ALDH1A1
SCHEMBL21473044 0.83 HSD17B10 (0.35) KDM4EATML3MBTL1KMT2APOLB
SCHEMBL21473048 0.80 KDM4E (0.43) KDM4EATML3MBTL1DUSP3KMT2A
SCHEMBL23814042 0.80 ATM (0.40) KDM4EATML3MBTL1KMT2AIL1R1
SCHEMBL21366953 0.80 KDM4E (0.38) KDM4EATML3MBTL1DUSP3KMT2A
SCHEMBL23823766 0.80 ATM (0.41) KDM4EATML3MBTL1DUSP3KMT2A
SCHEMBL24078682 0.79 ATM (0.39) KDM4EATML3MBTL1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 KDM4E 4292/4885ATM 4281/4885L3MBTL1 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.