SCHEMBL21473510

SCHEMBL21473510

CCCCNc1c(N(CC)CC)c(=S)c1=O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
MAPT P10636 3/20 0.35
KDM4E B2RXH2 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
GAA P10253 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.31
MCL1 Q07820 1/20 0.31
APAF1 O14727 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21230882 0.95 GPR84 (0.33) ALDH1A1MAPTL3MBTL1SMN1; SMN2MCL1
SCHEMBL22649776 0.90 GAA (0.30) GAA
SCHEMBL22645965 0.87 ALDH1A1 (0.35) ALDH1A1MAPTKDM4EL3MBTL1GAA
SCHEMBL21842648 0.85 ALDH1A1 (0.35) ALDH1A1MAPTKDM4EL3MBTL1GAA
SCHEMBL22645839 0.85 ALDH1A1 (0.36) ALDH1A1MAPTKDM4EL3MBTL1GAA
SCHEMBL21472512 0.84
SCHEMBL23268308 0.84 SMN1; SMN2 (0.36) ALDH1A1MAPTL3MBTL1TDP1SMN1; SMN2
SCHEMBL21472528 0.84 ALDH1A1 (0.40) ALDH1A1MAPTKDM4EL3MBTL1GAA
SCHEMBL21472309 0.83
SCHEMBL24937871 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020227537-A1 DIFFERENTIALLY EXPRESSED IMMUNE CELL MICRORNAS FOR REGULATION OF PROTEIN EXPRESSION Modernatx, Inc (US) 2020-11-12 WO disclosed
US-20190314291-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS MODERNATX, INC. 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190314291-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS LCP2, CD14, MYD88 ALDH1A1 4722/4885MAPT 2204/4885KDM4E 4100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.