Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19033715 | 0.84 | MEN1 (0.33) | — | |
| SCHEMBL14051676 | 0.80 | MEN1 (0.31) | — | |
| SCHEMBL10487352 | 0.78 | TDP1 (0.31) | TDP1 | |
| SCHEMBL19033675 | 0.75 | ARG1 (0.33) | — | |
| SCHEMBL24737703 | 0.73 | — | — | |
| SCHEMBL19510058 | 0.73 | — | — | |
| SCHEMBL21473597 | 0.73 | NCF1 (0.34) | ALDH1A1TSHRTDP1 | |
| SCHEMBL26064874 | 0.73 | — | — | |
| SCHEMBL14212686 | 0.73 | KDM4E (0.39) | TDP1 | |
| SCHEMBL2673779 | 0.73 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778586-A1 | QUINAZOLINE COMPOUND SERVING AS EGFR TRIPLE MUTATION INHIBITOR AND APPLICATIONS THEREOF | East China University of Science and Technology (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019196938-A1 | QUINAZOLINE COMPOUND SERVING AS EGFR TRIPLE MUTATION INHIBITOR AND APPLICATIONS THEREOF | 华东理工大学 | 2019-10-17 | — | — | WO | disclosed |