Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.72 |
| ▸ | CTSS | P25774 | 4/20 | 0.67 |
| ▸ | CTSK | P43235 | 3/20 | 0.67 |
| ▸ | CTSB | P07858 | 2/20 | 0.67 |
| ▸ | CTSL | P07711 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84524 | 1.00 | KLK5 (0.72) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL1196457 | 1.00 | KLK5 (0.72) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL6292728 | 1.00 | KLK5 (0.72) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL20030598 | 0.95 | CTSS (0.68) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL17138017 | 0.95 | CTSS (0.68) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL27507036 | 0.95 | CTSS (0.68) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL7896684 | 0.95 | KLK5 (0.67) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL30135036 | 0.95 | CTSS (0.68) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL17138015 | 0.95 | CTSS (0.68) | KLK5CTSSCTSKCTSBCTSL | |
| SCHEMBL6051752 | 0.95 | CTSS (0.68) | KLK5CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190314444-A1 | ETBR ANTAGONIST COMPOUNDS, COMPOSITIONS, AND USES | ENB THERAPEUTICS, INC. | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314444-A1 | ETBR ANTAGONIST COMPOUNDS, COMPOSITIONS, AND USES | EDNRB, EDNRA, LTB4R | KLK5 495/4885CTSS 1179/4885CTSK 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.