SCHEMBL84524

SCHEMBL84524

COC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KLK5 Q9Y337 2/20 0.72
CTSS P25774 4/20 0.67
CTSK P43235 3/20 0.67
CTSB P07858 2/20 0.67
CTSL P07711 1/20 0.67
ACE P12821 1/20 0.64
ATM Q13315 2/20 0.60
ALDH1A1 P00352 3/20 0.59
THRB P10828 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
HSD17B10 Q99714 1/20 0.59
POLB P06746 1/20 0.58
AKT1 P31749 1/20 0.58
EPHX2 P34913 1/20 0.57
LMNA P02545 2/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
GLA P06280 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1196457 1.00 KLK5 (0.72) KLK5CTSSCTSKCTSBCTSL
SCHEMBL21473748 1.00 KLK5 (0.72) KLK5CTSSCTSKCTSBCTSL
SCHEMBL6292728 1.00 KLK5 (0.72) KLK5CTSSCTSKCTSBCTSL
SCHEMBL20030598 0.95 CTSS (0.68) KLK5CTSSCTSKCTSBCTSL
SCHEMBL17138017 0.95 CTSS (0.68) KLK5CTSSCTSKCTSBCTSL
SCHEMBL27507036 0.95 CTSS (0.68) KLK5CTSSCTSKCTSBCTSL
SCHEMBL7896684 0.95 KLK5 (0.67) KLK5CTSSCTSKCTSBCTSL
SCHEMBL30135036 0.95 CTSS (0.68) KLK5CTSSCTSKCTSBCTSL
SCHEMBL17138015 0.95 CTSS (0.68) KLK5CTSSCTSKCTSBCTSL
SCHEMBL6051752 0.95 CTSS (0.68) KLK5CTSSCTSKCTSBCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116046861-A Manufacturing method of electrochemical sensor for promoting electron transfer 深圳可孚生物科技有限公司 2023-05-02 CN claimed
CN-110724112-A Bisoxazoline ligand compound and synthetic method thereof 五邑大学 2020-01-24 CN claimed
WO-2016126572-A2 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS AND THERAPEUTIC METHODS USING THE SAME THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2016-08-11 WO claimed
US-5876492-A Ink compositions containing esters XEROX CORPORATION (US) 1999-03-02 US claimed
EP-3650464-B1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND SHANGPHARMA INNOVATION INC (US) 2025-11-05 EP disclosed
US-20250162989-A1 USP30 INHIBITORS AND USES THEREOF VINCERE BIOSCIENCES, INC. 2025-05-22 US disclosed
US-20250110407-A1 SEMICONDUCTOR SUBSTRATE MANUFACTURING METHOD, AND RESIST BASE FILM FORMING COMPOSITION JSR CORPORATION (JP) 2025-04-03 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240142876-A1 SEMICONDUCTOR SUBSTRATE MANUFACTURING METHOD AND COMPOSITION JSR CORPORATION (JP) 2024-05-02 US disclosed
CN-117903044-A Pyridine-2-alkynyl carbonyl compound and preparation method and application thereof 华中师范大学 2024-04-19 CN disclosed
CN-117836270-A USP30 inhibitors and uses thereof 文森雷生物科学股份有限公司 2024-04-05 CN disclosed
US-20240105451-A1 SEMICONDUCTOR SUBSTRATE MANUFACTURING METHOD AND COMPOSITION JSR CORPORATION (JP) 2024-03-28 US disclosed
US-4837349-A Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same SUNTORY LIMITED (JP) 1989-06-06 US disclosed
US-4820712-A Sparsomycin (SC-RS) compounds having antitumor activity, a process for their preparation and pharmaceutical compositions containing sparsomycin (SC-RS) compounds STICHTING KATHOLIEKE UNIVERSITEIT (NL) 1989-04-11 US disclosed
US-4729985-A Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues PFIZER INC. (US) 1988-03-08 US disclosed
US-4668769-A Oxa- and azahomocyclostatine polypeptides PFIZER INC. 1987-05-26 US disclosed
EP-0217243-A2 Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same SUNTORY LIMITED (JP) 1987-04-08 EP disclosed
EP-0212903-A2 Polypeptide derivatives containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues PFIZER INC. (US) 1987-03-04 EP disclosed
EP-0211580-A2 Renin inhibiting polypeptides and intermediates therefor PFIZER INC. (US) 1987-02-25 EP disclosed
US-4599198-A Intermediates in polypeptide synthesis PFIZER INC. (US) 1986-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250162989-A1 USP30 INHIBITORS AND USES THEREOF USP30, USP28, USP1 KLK5 3639/4885CTSS 2213/4885CTSK 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.