Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 5/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | BRD2 | P25440 | 2/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.31 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24699291 | 0.86 | CYP1A2 (0.35) | MAOBMAOACYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL21473900 | 0.85 | CYP1A2 (0.34) | MAOBMAOACYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL24699688 | 0.84 | PRKDC (0.34) | CYP1A2PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL21475590 | 0.83 | CYP1A2 (0.32) | CYP1A2CYP2A6ALDH1A1CYP3A4TSHR | |
| SCHEMBL21475610 | 0.82 | CYP1A2 (0.34) | MAOBCYP1A2CYP2A6ALDH1A1KDM4E | |
| SCHEMBL23919352 | 0.81 | ADORA3 (0.35) | MAOBMAOAPRKDCPIK3CDPIK3CA | |
| SCHEMBL24699017 | 0.81 | ALDH1A1 (0.33) | MAOBMAOACYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL16203794 | 0.81 | ALDH1A1 (0.32) | ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL4089241 | 0.81 | PRKDC (0.33) | CYP1A2PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL30646703 | 0.81 | PRKDC (0.33) | CYP1A2PRKDCPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | SLC7A1, WEE1, SLC7A5 | MAOB 36/4885MAOA 50/4885CYP1A2 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.