SCHEMBL23919352

SCHEMBL23919352

Cc1ccc2c(oc3c(C)cccc32)c1N(c1ccccc1-c1ccccc1)c1ccc2ccc3c(N(c4ccccc4-c4ccccc4)c4c(C)ccc5c4oc4c(C)cccc45)ccc4ccc1c2c43

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PIK3CD O00329 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
PIK3CG P48736 1/20 0.30
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16216596 0.90 ADORA3 (0.37) ADORA3ADORA2AADORA1MAOAMAOB
SCHEMBL23919449 0.89 CYP1A1 (0.33) TSHRPIK3CDPIK3CBPRKDC
SCHEMBL23919266 0.89
SCHEMBL23919350 0.86 MAOA (0.33) ADORA3ADORA2AADORA1MAOAMAOB
SCHEMBL23919351 0.85 ALDH1A1 (0.36) MAOAMAOBALDH1A1CYP3A4HPGD
SCHEMBL18776737 0.85 ALDH1A1 (0.36) ADORA3ADORA2AADORA1ALDH1A1CYP3A4
SCHEMBL23919346 0.84 MAOA (0.34) ADORA3ADORA2AADORA1MAOAMAOB
SCHEMBL23919312 0.83 HPGD (0.33) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL16203773 0.83 CYP17A1 (0.34) ADORA3ADORA2AADORA1MAOAMAOB
SCHEMBL23919332 0.83 GPR55 (0.35) ADORA3ADORA2AADORA1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE OLA1, TAS2R19, TMEM109 ADORA3 1825/4885ADORA2A 1501/4885ADORA1 683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.