Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473906 | 0.94 | — | — | |
| SCHEMBL4078994 | 0.86 | ALOX5 (0.34) | PLA2G2APLA2G4AALOX5PLA2G10 | |
| SCHEMBL21473909 | 0.86 | ALOX5 (0.35) | PLA2G2APLA2G4AALOX5PLA2G10 | |
| SCHEMBL15045816 | 0.84 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL4084608 | 0.84 | ALOX5 (0.34) | PLA2G2APLA2G4AALOX5PLA2G10 | |
| SCHEMBL4079924 | 0.84 | ALOX5 (0.36) | ALOX5 | |
| SCHEMBL24699046 | 0.84 | RARA (0.31) | — | |
| SCHEMBL23849121 | 0.83 | ALOX5 (0.40) | PLA2G2APLA2G4AALOX5PLA2G10 | |
| SCHEMBL4078982 | 0.83 | PLA2G2A (0.32) | PLA2G2APLA2G4AALOX5PLA2G10 | |
| SCHEMBL4084612 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | SLC7A1, WEE1, SLC7A5 | PLA2G2A 4400/4885PLA2G4A 4459/4885ALOX5 622/4885 |
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | SLC7A1, WEE1, SLC7A5 | PLA2G2A 4400/4885PLA2G4A 4459/4885ALOX5 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.