SCHEMBL21473929

SCHEMBL21473929

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)c3ccc5c6cc(-n7c8ccccc8c8ccccc87)ccc6c6cccc7c6c5c3n47)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RAC2 P15153 1/20 0.33
RAC3 P60763 1/20 0.33
CDC42 P60953 1/20 0.33
RAC1 P63000 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PTGER4 P35408 1/20 0.31
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21473927 0.94 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL21472984 0.90 MEN1 (0.34) KDM4EATML3MBTL1PTGER4NPY5R
SCHEMBL21473077 0.88 KDM4E (0.34) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL21472982 0.87 TSPO (0.34) KDM4EATML3MBTL1NPY5R
SCHEMBL15786011 0.87 KDM4E (0.42) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL15786048 0.87 KDM4E (0.42) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL15786047 0.87 KDM4E (0.42) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL21473031 0.87 KDM4E (0.39) KDM4EATML3MBTL1
SCHEMBL15786009 0.87 KDM4E (0.42) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL15786057 0.87 KDM4E (0.42) RAC2RAC3CDC42RAC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 RAC2 2420/4885RAC3 2543/4885CDC42 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.