SCHEMBL21472984

SCHEMBL21472984

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)c3ccc5c6ccccc6c6cccc7c6c5c3n47)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.34
KMT2A Q03164 6/20 0.34
ALDH1A1 P00352 4/20 0.34
MAPT P10636 3/20 0.34
HPGD P15428 3/20 0.34
KDM4E B2RXH2 3/20 0.33
LMNA P02545 2/20 0.33
ATM Q13315 1/20 0.33
GLA P06280 1/20 0.33
NPY5R Q15761 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
NTSR1 P30989 1/20 0.31
CYP1A2 P05177 3/20 0.31
CYP3A4 P08684 3/20 0.31
CYP2C9 P11712 3/20 0.31
HSD17B10 Q99714 3/20 0.31
CYP2D6 P10635 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21472982 0.96 TSPO (0.34) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21473929 0.90 RAC2 (0.33) KDM4EATMNPY5RL3MBTL1PTGER4
SCHEMBL20444630 0.89 CYP1A2 (0.35) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20444627 0.89 CYP1A2 (0.35) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21453767 0.88 NPY5R (0.38) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21472981 0.88 TSPO (0.38) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21472980 0.88 TSPO (0.38) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21454090 0.87 NPY5R (0.31) HPGDKDM4ELMNANPY5RTP53
SCHEMBL21453484 0.87 ADORA2A (0.32) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21453474 0.87 NPY5R (0.38) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 MEN1 2886/4885KMT2A 4482/4885ALDH1A1 1398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.