Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | USP8 | P40818 | 1/20 | 0.30 |
| ▸ | USP5 | P45974 | 1/20 | 0.30 |
| ▸ | USP4 | Q13107 | 1/20 | 0.30 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890353 | 0.81 | USP2 (0.32) | USP2USP8USP5USP4USP7 | |
| SCHEMBL20228237 | 0.81 | CYP11B1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL18499523 | 0.81 | CYP11B1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL20228328 | 0.80 | NFE2L2 (0.54) | — | |
| SCHEMBL21399534 | 0.80 | NFE2L2 (0.54) | — | |
| SCHEMBL23395480 | 0.79 | RAPGEF4 (0.30) | RAPGEF4 | |
| SCHEMBL24940737 | 0.78 | ALDH1A1 (0.30) | ALDH1A1MAPTHTT | |
| SCHEMBL21399529 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL19465072 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL24940712 | 0.77 | USP2 (0.30) | USP2USP8USP5USP4USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982730-B1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2019-10-16 | — | — | EP | disclosed |
| WO-2017137145-A1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | WO | disclosed |