Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.42 |
| ▸ | SLC6A15 | Q9H2J7 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474573 | 0.92 | ALDH1A1 (0.41) | HRH1SLC6A15MAPTALOX15MEN1 | |
| SCHEMBL21474668 | 0.83 | POLB (0.39) | SLC6A15MAPTALOX15MEN1KMT2A | |
| SCHEMBL21474672 | 0.81 | MAPK14 (0.42) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL21474575 | 0.81 | ALDH1A1 (0.41) | SLC6A15MAPTALOX15MEN1KMT2A | |
| SCHEMBL21474555 | 0.79 | ALDH1A1 (0.40) | MAPTMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL21478248 | 0.75 | MAPT (0.40) | MAPTALOX15MEN1KMT2ANPSR1 | |
| SCHEMBL21474571 | 0.73 | MAPK1 (0.42) | ALOX15MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL21478257 | 0.73 | ALDH1A1 (0.49) | MAPTALOX15MEN1KMT2ANPSR1 | |
| SCHEMBL25549318 | 0.72 | KDM4E (0.45) | SLC6A15MAPTALOX15MEN1KMT2A | |
| SCHEMBL9571031 | 0.71 | ALDH1A1 (0.43) | HRH1SLC6A15MAPTALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |