Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474668 | 0.90 | POLB (0.39) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL21474573 | 0.88 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL21474579 | 0.81 | HRH1 (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL21474555 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL25549318 | 0.76 | KDM4E (0.45) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL21474672 | 0.75 | MAPK14 (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL21465477 | 0.71 | TUBB4A (0.67) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL21478257 | 0.70 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL21478248 | 0.69 | MAPT (0.40) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL25600261 | 0.67 | ALDH1A1 (0.43) | ALDH1A1KMT2AKDM4EHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |