Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474580 | 0.84 | SLC6A3 (0.44) | SLC6A3SLC6A2HSD17B3MEN1KMT2A | |
| SCHEMBL12447830 | 0.84 | SLC6A3 (0.44) | SLC6A3SLC6A2HSD17B3MEN1KMT2A | |
| SCHEMBL21474599 | 0.83 | MAPK14 (0.42) | SLC6A3MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL21478271 | 0.75 | SLC6A3 (0.40) | SLC6A3HSD17B3MEN1KMT2AABL1 | |
| SCHEMBL21478254 | 0.70 | MAOB (0.39) | SLC6A3MEN1KMT2AMAPTLMNA | |
| SCHEMBL25549318 | 0.69 | KDM4E (0.45) | SLC6A3SLC6A2MEN1KMT2AALDH1A1 | |
| SCHEMBL23058960 | 0.69 | MAPK14 (0.58) | HSD17B3 | |
| SCHEMBL27617877 | 0.68 | ALDH1A1 (0.56) | SLC6A3SLC6A2KMT2AALDH1A1MAPT | |
| SCHEMBL12447837 | 0.68 | SRD5A1 (0.49) | HSD17B3ALDH1A1HTT | |
| SCHEMBL10932406 | 0.68 | ALDH1A1 (0.52) | SLC6A3SLC6A2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |