Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474588 | 0.83 | SLC6A3 (0.46) | KDM4EALDH1A1HPGDL3MBTL1SLC6A4 | |
| SCHEMBL16996610 | 0.78 | KDM4E (0.45) | MAPK14KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL12050825 | 0.74 | MAPK14 (0.68) | MAPK14KDM4EPARP1 | |
| SCHEMBL13548810 | 0.71 | MAPK14 (0.71) | MAPK14 | |
| SCHEMBL15094887 | 0.71 | PARP1 (0.40) | MAPK14KDM4EALDH1A1GAARAB9A | |
| SCHEMBL25668011 | 0.70 | ALPL (0.40) | MAPK14KDM4EALDH1A1GAAPDK2 | |
| SCHEMBL25598740 | 0.69 | MAPK14 (0.45) | MAPK14KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL27617877 | 0.68 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDL3MBTL1GAA | |
| SCHEMBL10932406 | 0.68 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDL3MBTL1GAA | |
| SCHEMBL12389716 | 0.68 | CA12 (0.47) | MAPK14KDM4EALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |