Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474595 | 0.71 | TSHR (0.42) | LTB4RLTB4R2HTTCYP3A4CYP2C9 | |
| SCHEMBL21474594 | 0.69 | LTA4H (0.41) | EPHX2HTTFFAR1NPSR1L3MBTL1 | |
| SCHEMBL21478277 | 0.68 | CYP26A1 (0.39) | LTB4RLTB4R2EPHX2HTTL3MBTL1 | |
| SCHEMBL21478274 | 0.65 | SLC6A3 (0.39) | LTB4RLTB4R2NPSR1LMNA | |
| SCHEMBL21723102 | 0.64 | ABL1 (0.54) | HTTCYP3A4CYP2C9CYP2C19NPSR1 | |
| SCHEMBL30974620 | 0.62 | L3MBTL1 (0.58) | HTTCYP3A4CYP2C9CYP2C19P2RX4 | |
| SCHEMBL5362837 | 0.62 | L3MBTL1 (0.58) | HTTCYP3A4CYP2C9CYP2C19P2RX4 | |
| SCHEMBL21478254 | 0.62 | MAOB (0.39) | LTB4RLTB4R2POLBLMNA | |
| SCHEMBL27915348 | 0.61 | HTR2A (0.47) | LMNA | |
| SCHEMBL21474683 | 0.61 | MAOB (0.40) | LTB4RLTB4R2FFAR1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |