SCHEMBL21474789

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21736354	0.89	TSHR (0.40)	MAPTTSHRNPSR1ALDH1A1LMNA
	SCHEMBL21736371	0.88	CYP1A2 (0.33)	MAPTTSHRALDH1A1LMNAHSD17B10
	SCHEMBL21736415	0.87	TSHR (0.38)	MAPTTSHRNPSR1ALDH1A1LMNA
	SCHEMBL16905860	0.86	MAPT (0.41)	MAPTTSHRNPSR1ALDH1A1LMNA
	SCHEMBL21736059	0.86	TSHR (0.39)	MAPTTSHRNPSR1ALDH1A1LMNA
	SCHEMBL18273168	0.85	MAPT (0.43)	MAPTTSHRNPSR1ALDH1A1LMNA
	SCHEMBL19247884	0.85	TSHR (0.45)	MAPTTSHRNPSR1ALDH1A1LMNA
	SCHEMBL19246950	0.85	TSHR (0.45)	MAPTTSHRNPSR1ALDH1A1LMNA
	SCHEMBL26415871	0.84	MAPT (0.37)	MAPTTSHRNPSR1ALDH1A1LMNA
	SCHEMBL21736006	0.84	TSHR (0.38)	MAPTTSHRNPSR1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.