Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24761803 | 0.77 | HMGCR (0.31) | HMGCR | |
| SCHEMBL9908615 | 0.66 | ADRB2 (0.44) | ADRB2ADRB1ADRB3 | |
| SCHEMBL25147626 | 0.66 | ADRB2 (0.44) | ADRB2ADRB1ADRB3 | |
| SCHEMBL99223 | 0.65 | GABRA1 (0.54) | ADRB2ADRB1ADRB3 | |
| SCHEMBL24450880 | 0.65 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL22924942 | 0.65 | ADRB2 (0.43) | ADRB2ADRB1ADRB3 | |
| SCHEMBL12331424 | 0.64 | POLB (0.45) | — | |
| SCHEMBL31522451 | 0.64 | ADRB2 (0.41) | ADRB2ADRB1ADRB3 | |
| SCHEMBL24743652 | 0.62 | ADRB2 (0.41) | ADRB2ADRB1ADRB3 | |
| SCHEMBL2302293 | 0.62 | MGAM (0.38) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190315687-A1 | Substituted Pyrrolidines and Methods of Use | ABBVIE S.Á.R.L. (LU) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315687-A1 | Substituted Pyrrolidines and Methods of Use | CFTR, PKD1, PKD2 | ADRB2 621/4885ADRB1 515/4885ADRB3 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.