Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.52 |
| ▸ | SYK | P43405 | 4/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21476713 | 0.89 | FFAR1 (0.64) | FFAR1SYKCYP4F2CYP4A11FFAR4 | |
| SCHEMBL901475 | 0.82 | CYP4F2 (0.55) | SYKCYP4F2CYP4A11 | |
| SCHEMBL8903063 | 0.81 | TDP1 (0.56) | FFAR1SYKCYP4F2CYP4A11FFAR4 | |
| SCHEMBL4425984 | 0.80 | CYP4F2 (0.64) | SYKCYP4F2CYP4A11 | |
| SCHEMBL21475923 | 0.79 | HTR7 (0.57) | FFAR1SYKCYP4F2CYP4A11FFAR4 | |
| SCHEMBL30540945 | 0.79 | FFAR1 (0.55) | FFAR1SYKCYP4F2CYP4A11 | |
| SCHEMBL9444904 | 0.78 | SYK (0.49) | FFAR1SYKCYP4F2CYP4A11 | |
| SCHEMBL21476702 | 0.77 | FFAR1 (0.66) | FFAR1FFAR4 | |
| SCHEMBL1746644 | 0.76 | FFAR1 (0.79) | FFAR1FFAR4 | |
| SCHEMBL5114673 | 0.76 | FFAR1 (0.70) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200202-A1 | ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7) | MORPHIC THERAPEUTIC, INC. (US) | 2019-10-17 | — | — | WO | disclosed |