Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.70 |
| ▸ | ITGAV | P06756 | 6/20 | 0.70 |
| ▸ | NCF1 | P14598 | 5/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.39 |
| ▸ | CYBB | P04839 | 1/20 | 0.38 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100942 | 0.96 | ITGB3 (0.70) | ITGB3ITGAVNCF1ABCG2CYBB | |
| SCHEMBL21064809 | 0.95 | ITGB3 (0.77) | ITGB3ITGAVNCF1ABCG2CYBB | |
| SCHEMBL21475355 | 0.84 | ITGB3 (0.60) | ITGB3ITGAVNCF1ABCG2ABCC1 | |
| SCHEMBL29107238 | 0.84 | ITGB3 (0.61) | ITGB3ITGAVFOLH1THRATHRB | |
| SCHEMBL23868262 | 0.84 | ITGB3 (0.71) | ITGB3ITGAVABCG2MMP2MMP9 | |
| SCHEMBL21100765 | 0.81 | ITGB3 (0.60) | ITGB3ITGAVNCF1ABCG2ABCC1 | |
| SCHEMBL21100766 | 0.80 | ITGB3 (0.64) | ITGB3ITGAVABCG2ABCC1 | |
| SCHEMBL19677591 | 0.79 | ITGB3 (0.71) | ITGB3ITGAVNCF1CYBBNOX5 | |
| SCHEMBL23984251 | 0.75 | ITGB3 (0.52) | ITGB3ITGAVTHRATHRBRXRA | |
| SCHEMBL21100868 | 0.75 | ITGB3 (0.55) | ITGB3ITGAVTHRATHRBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190314314-A1 | COMPOSITION AND METHOD FOR DUAL TARGETING IN TREATMENT OF NEUROENDOCRINE TUMORS | NANOPHARMACEUTICALS, LLC | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314314-A1 | COMPOSITION AND METHOD FOR DUAL TARGETING IN TREATMENT OF NEUROENDOCRINE TUMORS | THRB, TSHR, SLC6A2 | ITGB3 12/4885ITGAV 14/4885NCF1 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.