Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.71 |
| ▸ | ITGAV | P06756 | 6/20 | 0.71 |
| ▸ | THRB | P10828 | 5/20 | 0.47 |
| ▸ | THRA | P10827 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19677585 | 0.85 | ITGB3 (0.53) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL19677575 | 0.85 | ITGB3 (0.61) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL19708683 | 0.83 | THRB (0.57) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL21064809 | 0.82 | ITGB3 (0.77) | ITGB3ITGAVNCF1CYBBNOX5 | |
| SCHEMBL23868262 | 0.81 | ITGB3 (0.71) | ITGB3ITGAV | |
| SCHEMBL21479481 | 0.79 | ITGB3 (0.70) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL21100942 | 0.79 | ITGB3 (0.70) | ITGB3ITGAVNCF1CYBBNOX5 | |
| SCHEMBL19708684 | 0.79 | ITGB3 (0.55) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL21100766 | 0.77 | ITGB3 (0.64) | ITGB3ITGAV | |
| SCHEMBL23984251 | 0.77 | ITGB3 (0.52) | ITGB3ITGAVTHRBTHRAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348425-A1 | NON-CLEAVABLE POLYMER CONJUGATED WITH ALPHA V BETA 3 INTEGRIN THYROID ANTAGONISTS | NANOPHARMACEUTICALS, LLC | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348425-A1 | NON-CLEAVABLE POLYMER CONJUGATED WITH ALPHA V BETA 3 INTEGRIN THYROID ANTAGONISTS | THRA, CD44, ITGAV | ITGB3 4/4885ITGAV 3/4885THRB 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.