SCHEMBL21479554

SCHEMBL21479554

Cc1c(C(F)(F)F)csc1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26713887 0.76
SCHEMBL21241126 0.73 CYP1A2 (0.34) MEN1GAAMAPTKMT2ANPSR1
SCHEMBL21479556 0.71
SCHEMBL21479555 0.71 MEN1 (0.32) MEN1GAAMAPTKMT2ANPSR1
SCHEMBL20666014 0.70
SCHEMBL23960271 0.70 MEN1 (0.31) MEN1GAAMAPTKMT2ANPSR1
SCHEMBL26740569 0.70 HPGD (0.33) MEN1GAAMAPTKMT2ANPSR1
SCHEMBL13714083 0.70 MEN1 (0.31) MEN1GAAMAPTKMT2ANPSR1
SCHEMBL22513573 0.69 CNR1 (0.35)
SCHEMBL13333995 0.69 GABRA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634445-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-04-25 US disclosed
US-20200369699-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-26 US disclosed
US-20190315788-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200369699-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, SOD1 MEN1 1453/4885GAA 920/4885MAPT 2008/4885
US-20190315788-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, ZYX MEN1 281/4885GAA 2689/4885MAPT 3547/4885
US-11634445-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, SOD1 MEN1 1453/4885GAA 920/4885MAPT 2008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.