Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLQ | O75417 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21480111 | 0.88 | RAB9A (0.46) | NPC1KMT2AMEN1ALDH1A1GRM5 | |
| SCHEMBL22312249 | 0.88 | KMT2A (0.52) | NPC1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL21480027 | 0.81 | ALDH1A1 (0.49) | NPC1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL6702666 | 0.81 | TSHR (0.56) | NPC1KMT2AALDH1A1LMNAGRM5 | |
| SCHEMBL21480037 | 0.79 | KMT2A (0.50) | NPC1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL1019064 | 0.78 | PPIB (0.52) | KMT2AMEN1GAAALDH1A1RAB9A | |
| SCHEMBL9622282 | 0.78 | NPC1 (0.52) | NPC1ALDH1A1LMNAGRM5RAB9A | |
| SCHEMBL1987313 | 0.77 | TSHR (0.52) | NPC1KMT2AALDH1A1LMNAGRM5 | |
| SCHEMBL1760632 | 0.77 | KMT2A (0.58) | NPC1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL476827 | 0.77 | TSHR (0.61) | NPC1KMT2AALDH1A1LMNAGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019196262-A1 | PREPARATION METHOD FOR HEXAHYDROFURO-FURAN-OL DERIVATIVE, AND INTERMEDIATE OF DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏瑞科医药科技有限公司 | 2019-10-17 | — | — | WO | disclosed |