SCHEMBL21480652

SCHEMBL21480652

c1ccc(-c2ccc(-c3cc(-c4ccc(-c5cc6ccccc6o5)cc4)nc(-c4ccc5c(c4)oc4ccccc45)n3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.48
PLA2G2A P14555 4/20 0.45
PLA2G4A P47712 4/20 0.45
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
TNKS O95271 2/20 0.44
NPC1 O15118 2/20 0.44
CYP19A1 P11511 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 2/20 0.44
ABCG2 Q9UNQ0 2/20 0.44
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
CA12 O43570 1/20 0.44
TP53 P04637 1/20 0.44
ABCB1 P08183 1/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21476552 0.95 PLA2G2A (0.48) MAOBPLA2G2APLA2G4ACA1CA2
SCHEMBL23335209 0.95 CYP19A1 (0.43) MAOBPLA2G2APLA2G4ACA1CA2
SCHEMBL23334474 0.94 PLA2G2A (0.43) MAOBPLA2G2APLA2G4ACA1CA2
SCHEMBL21476415 0.92 MAOB (0.50) MAOBPLA2G2APLA2G4ACA1CA2
SCHEMBL21476563 0.92 MAOB (0.43) MAOBPLA2G2APLA2G4ACA1CA2
SCHEMBL21109833 0.89 MEN1 (0.49) PLA2G2APLA2G4ASMN1; SMN2HPGDMEN1
SCHEMBL21109050 0.89 MEN1 (0.49) PLA2G2APLA2G4ASMN1; SMN2HPGDMEN1
SCHEMBL21476376 0.89 PLA2G2A (0.43) MAOBPLA2G2APLA2G4ANPC1CYP19A1
SCHEMBL21476380 0.89 CYP19A1 (0.41) MAOBPLA2G2APLA2G4ACA1CA2
SCHEMBL21476622 0.89 PLA2G2A (0.51) MAOBPLA2G2APLA2G4ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210130336-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-05-06 US disclosed
WO-2019198806-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2019-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210130336-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE L1CAM, MLX, LEF1 MAOB 2115/4885PLA2G2A 3064/4885PLA2G4A 4054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.