Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.61 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.61 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.61 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.61 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.61 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.61 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | TACR2 | P21452 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SHBG | P04278 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11846534 | 0.98 | ALDH1A1 (0.59) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| Sulfuric Acid SCHEMBL5433105 | 0.94 | ESR1 (0.68) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| Sulfuric Acid SCHEMBL28298994 | 0.93 | ESR1 (0.66) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL548500 | 0.91 | ESR1 (0.73) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| Sulfuric Acid SCHEMBL1101445 | 0.89 | ESR1 (0.78) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL324185 | 0.89 | ESR1 (0.70) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| Sulfuric Acid SCHEMBL11228881 | 0.87 | PTGS2 (0.81) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| Sulfuric Acid SCHEMBL371313 | 0.87 | ESR1 (0.75) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9001679 | 0.87 | ESR1 (0.63) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| 4-Nonylphenol SCHEMBL2183411 | 0.87 | PTGS2 (0.81) | ALDH1A1ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541153-B2 | Toner for developing electrostatic image, developer for electrostatic image, toner cartridge, process cartridge, image forming method, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| EP-1760533-B1 | Binder resin for electrostatic image developing toner, binder resin liquid dispersion for electrostatic image developing toner, electrostatic image developing toner, and production processes thereof | FUJI XEROX CO LTD (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-8288071-B2 | Resin particle liquid dispersion for electrostatic image developing toner, electrostatic image developing toner, production method thereof, developer and image forming method | FUJI XEROX CO., LTD. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-7981583-B2 | Binder resin for electrostatic image developing toner, binder resin particle liquid dispersion for electrostatic image developing toner, production method of electrostatic image developing toner, electrostatic image developing toner, electrostatic image developer, image forming method and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20110171572-A1 | TONER FOR DEVELOPING ELECTROSTATIC IMAGE, DEVELOPER FOR ELECTROSTATIC IMAGE, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20090297977-A1 | Resin particle liquid dispersion for electrostatic image developing toner, electrostatic image developing toner, production method thereof, developer and image forming method | FUJI XEROX CO., LTD. (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090162778-A1 | BINDER RESIN FOR ELECTROSTATIC IMAGE DEVELOPING TONER, BINDER RESIN PARTICLE LIQUID DISPERSION FOR ELECTROSTATIC IMAGE DEVELOPING TONER, PRODUCTION METHOD OF ELECTROSTATIC IMAGE DEVELOPING TONER, ELECTROSTATIC IMAGE DEVELOPING TONER, ELECTROSTATIC IMAGE DEVELOPER, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2009-06-25 | — | — | US | disclosed |
| US-7547500-B2 | Binder resin for electrostatic image developing toner, binder resin liquid dispersion for electrostatic image developing toner, electrostatic image developing toner, and production processes thereof | FUJI XEROX CO., LTD. (JP) | 2009-06-16 | — | — | US | disclosed |
| EP-1760533-A2 | Binder resin for electrostatic image developing toner, binder resin liquid dispersion for electrostatic image developing toner, electrostatic image developing toner, and production processes thereof | FUJI XEROX CO., LTD. (JP) | 2007-03-07 | — | — | EP | disclosed |
| US-20070048646-A1 | Binder resin for electrostatic image developing toner, binder resin liquid dispersion for electrostatic image developing toner, electrostatic image developing toner, and production processes thereof | FUJI XEROX CO., LTD. (JP) | 2007-03-01 | — | — | US | disclosed |
| US-20070020551-A1 | Resin particle liquid dispersion for electrostatic image developing toner, electrostatic image developing toner, production method thereof, developer and image forming method | FUJI XEROX CO., LTD. (JP) | 2007-01-25 | — | — | US | disclosed |