SCHEMBL2148123

SCHEMBL2148123

C=Cc1ccnc(C(=O)O)c1C=C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.42
ASPH Q12797 8/20 0.42
KDM8 Q8N371 8/20 0.42
MAPT P10636 4/20 0.40
ALDH1A1 P00352 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
BLM P54132 1/20 0.40
AGER Q15109 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CYP1A2 P05177 1/20 0.36
MYC P01106 1/20 0.33
KDM6B O15054 1/20 0.32
TET3 O43151 1/20 0.32
KDM4A O75164 1/20 0.32
BBOX1 O75936 1/20 0.32
KDM5A P29375 1/20 0.32
KDM5C P41229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28521418 0.81 KDM4E (0.46) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL18901936 0.80 MAPT (0.35) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL28802257 0.80 KDM4E (0.49) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL6566964 0.80 KDM4E (0.41) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL548552 0.76 KDM4E (0.43) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL754122 0.76 KDM4E (0.55) KDM4EASPHKDM8MAPTALDH1A1
Hydrochloric Acid SCHEMBL16239168 0.74 KDM4E (0.53) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL3677764 0.73 KDM4E (0.38) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL18901983 0.71 PDE3B (0.35) KDM4ENPSR1
SCHEMBL27775349 0.70 KDM4E (0.34) KDM4EASPHKDM8MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541153-B2 Toner for developing electrostatic image, developer for electrostatic image, toner cartridge, process cartridge, image forming method, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2013-09-24 US disclosed
US-20110171572-A1 TONER FOR DEVELOPING ELECTROSTATIC IMAGE, DEVELOPER FOR ELECTROSTATIC IMAGE, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2011-07-14 US disclosed
US-20060115757-A1 Toner for development of electrostatic latent image, electrostatic latent image developer, and method for formation of image FUJI XEROX CO., LTD. (JP) 2006-06-01 US disclosed
US-6582867-B2 A crystalline binder resin and a fatty acid ester or a resin having a contact angle with water that is smaller than that of the crystalline resin; electrography; reproducibility in particle size/distribution; low-temperature fixing; stability FUJI XEROX CO., LTD. (JP) 2003-06-24 US disclosed
US-20020055050-A1 Toner for developing electrostatic latent image, process for producing the same, and process for forming image FUJI XEROX CO., LTD. (JP) 2002-05-09 US disclosed