SCHEMBL6566964

SCHEMBL6566964

C=Cc1c(C)ccnc1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.41
ASPH Q12797 5/20 0.41
KDM8 Q8N371 5/20 0.41
MYC P01106 1/20 0.39
MAPT P10636 3/20 0.39
ALDH1A1 P00352 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
ALOX15 P16050 2/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
BLM P54132 1/20 0.39
AGER Q15109 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.35
LMNA P02545 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
P4HTM Q9NXG6 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2148123 0.80 KDM4E (0.42) KDM4EASPHKDM8MYCMAPT
SCHEMBL28802257 0.79 KDM4E (0.49) KDM4EASPHKDM8MYCMAPT
SCHEMBL15800572 0.79 CCR1 (0.31)
SCHEMBL28645262 0.77 KDM4E (0.38) KDM4EASPHKDM8MYCMAPT
SCHEMBL7199668 0.75 KDM4E (0.47) KDM4EASPHKDM8MYCMAPT
SCHEMBL15417589 0.74 CCR1 (0.39) L3MBTL1
SCHEMBL14284234 0.73 KDM4E (0.46) KDM4EASPHKDM8MYCMAPT
SCHEMBL9684174 0.73 KDM4E (0.50) KDM4EASPHKDM8MYCMAPT
SCHEMBL1541111 0.73 KDM4E (0.46) KDM4EASPHKDM8MYCMAPT
SCHEMBL30049082 0.73 KDM4E (0.50) KDM4EASPHKDM8MYCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1484381-A1 PHOSPHORS, PROCESS FOR PRODUCTION THEREOF, PHOSPHORESCENT COMPOSITIONS AND ARTICLES MADE BY USING THE SAME JSR Corporation (JP) 2004-12-08 EP disclosed
US-20040106006-A1 Phosphors, process for production thereof, phosphorescent compositions and articles made by using the same JSR CORPORATION (JP) 2004-06-03 US disclosed