Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ASPH | Q12797 | 6/20 | 0.49 |
| ▸ | KDM8 | Q8N371 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883713 | 0.80 | L3MBTL1 (0.42) | KDM4EASPHKDM8ALDH1A1ALOX15 | |
| SCHEMBL2148123 | 0.80 | KDM4E (0.42) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL6566964 | 0.79 | KDM4E (0.41) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL644769 | 0.75 | KDM4E (0.68) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL10373429 | 0.73 | KDM4E (0.60) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL28048186 | 0.73 | KDM4E (0.55) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL28337894 | 0.72 | KDM4E (0.58) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL28478885 | 0.72 | KDM4E (0.53) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL28177119 | 0.72 | KDM4E (0.53) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL28042315 | 0.71 | KDM4E (0.49) | KDM4EASPHKDM8MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102786480-A | 2-substituted-6-amino-5-alkyl, alkenyl or alkynyl-4-pyrimidinecarboxylic acids and 6-substituted-4-amino-3- alkyl, alkenyl or alkynyl picolinic acids and their use as herbicides | DOW AGROSCIENCES LLC | 2012-11-21 | — | — | CN | disclosed |