Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ASPH | Q12797 | 4/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 4/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148123 | 0.80 | KDM4E (0.42) | MAPTTSHRKDM4ENPSR1ASPH | |
| SCHEMBL6566964 | 0.76 | KDM4E (0.41) | MAPTTSHRKDM4ENPSR1ASPH | |
| SCHEMBL28802257 | 0.69 | KDM4E (0.49) | MAPTTSHRKDM4ENPSR1ASPH | |
| SCHEMBL28521418 | 0.67 | KDM4E (0.46) | MAPTTSHRKDM4ENPSR1ASPH | |
| SCHEMBL18089754 | 0.67 | THRA (0.40) | TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL548552 | 0.65 | KDM4E (0.43) | MAPTTSHRKDM4ENPSR1ASPH | |
| SCHEMBL27883713 | 0.65 | L3MBTL1 (0.42) | KDM4ENPSR1MAPK1ASPHKDM8 | |
| SCHEMBL23970772 | 0.63 | TDP1 (0.39) | KDM4ENPSR1MAPK1ASPHKDM8 | |
| SCHEMBL3677764 | 0.63 | KDM4E (0.38) | MAPTTSHRKDM4ENPSR1MAPK1 | |
| SCHEMBL25652150 | 0.63 | KDM4E (0.40) | TSHRKDM4EKDM6BKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |