SCHEMBL21481444

SCHEMBL21481444

c1ccc(-c2ccc(-n3c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5cc(-c6ccccc6)cc(-c6ccccc6)c5)cc4c4ncccc43)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSPO P30536 1/20 0.36
HDAC4 P56524 1/20 0.36
NPY5R Q15761 3/20 0.35
NR3C1 P04150 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
TOP1 P11387 2/20 0.33
DNM1 Q05193 1/20 0.33
AKR1C4 P17516 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
AKR1C1 Q04828 1/20 0.33
MMP2 P08253 1/20 0.33
ALK Q9UM73 2/20 0.32
PTGER4 P35408 1/20 0.32
RAC2 P15153 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21481416 0.98 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL15317269 0.96 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL21485493 0.95 KDM4E (0.39) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL17349397 0.95 KDM4E (0.45) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL21485453 0.94 ATM (0.40) KDM4EATML3MBTL1TSPONPY5R
SCHEMBL17349307 0.94 L3MBTL1 (0.47) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL17349395 0.93 KDM4E (0.44) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL18958770 0.93 KDM4E (0.44) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL11981062 0.92 KDM4E (0.49) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL17349310 0.91 L3MBTL1 (0.45) KDM4EATML3MBTL1TSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
US-20190319197-A1 ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190319197-A1 ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE PIEZO1, OR10J3, OR51E2 KDM4E 2904/4885ATM 2334/4885L3MBTL1 1968/4885
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF AOX1, ODC1, OTC KDM4E 4036/4885ATM 2511/4885L3MBTL1 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.