SCHEMBL2148152

SCHEMBL2148152

Cc1cc(Br)c(N=C=O)cc1N=C=O

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.50
TRPA1 O75762 1/20 0.50
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30301143 1.00 CYP3A4 (0.50) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL1045246 0.84 CYP3A4 (0.59) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL1483923 0.84 CYP3A4 (0.39) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL375132 0.82 CYP3A4 (0.57) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL1044718 0.82 CYP3A4 (0.61) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL1100599 0.80 ALDH1A1 (0.49) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL1191608 0.78 CYP3A4 (0.57) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL11618906 0.78 CYP3A4 (0.38) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL13893581 0.76 CYP3A4 (0.40) CYP3A4TRPA1
SCHEMBL78958 0.75 CYP3A4 (0.50) CYP3A4TRPA1ALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4791042-B2 2011-10-12 JP claimed
CN-1521197-B Polycarbodiimide having high index of refraction and production method thereof NITTO DENKO CORP 2010-04-07 CN claimed
EP-1569512-B1 PARTICULATE SUSPENSIONS SYNGENTA LTD (GB) 2007-02-28 EP claimed
US-20060116290-A1 Particulate suspensions SYNGENTA CROP PROTECTION, INC. 2006-06-01 US claimed
EP-1569512-A2 PARTICULATE SUSPENSIONS Syngenta Limited (GB) 2005-09-07 EP claimed
WO-2004052099-A2 PARTICULATE SUSPENSIONS SYNGENTA LIMITED (GB) 2004-06-24 WO claimed
WO-2003072625-A1 PHOTOCURABLE RESIN COMPOSITION FOR OPTICAL WAVEGUIDE AND OPTICAL WAVEGUIDE MADE OF THE SAME LUVANTIX CO., LTD. (KR) 2003-09-04 WO claimed
US-12227606-B2 Photocurable resin composition, photocurable resin article, and methods of fabricating the article THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-18 US disclosed
CN-113260332-B Photocurable resin composition, photocurable resin product, and method for producing product 加利福尼亚大学董事会 2023-04-07 CN disclosed
CN-113260332-A Photocurable resin composition, photocurable resin product, and method for producing product 加利福尼亚大学董事会 2021-08-13 CN disclosed
US-20210238335-A1 Photocurable Resin Composition, Photocurable Resin Article, and Methods of Fabricating the Article THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION 2021-08-05 US disclosed
WO-2020081891-A1 PHOTOCURABLE RESIN COMPOSITION, PHOTOCURABLE RESIN ARTICLE, AND METHODS OF FABRICATING THE ARTICLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-04-23 WO disclosed
EP-2750657-B1 BISUREA GELLING AGENTS AND COMPOSITIONS MILLIKEN & CO (US) 2018-03-21 EP disclosed
US-6749554-B1 Medical tools and devices with improved ultrasound visibility AMERSHAM PLC (GB) 2004-06-15 US disclosed
WO-2003072625-A1 PHOTOCURABLE RESIN COMPOSITION FOR OPTICAL WAVEGUIDE AND OPTICAL WAVEGUIDE MADE OF THE SAME LUVANTIX CO., LTD. (KR) 2003-09-04 WO disclosed
EP-0442013-B1 Isocyanate- and isothiocyanate-modified polysilazane ceramic precursors LANXIDE TECHNOLOGY CO LTD (US) 1996-06-05 EP disclosed
EP-0442013-A1 Isocyanate- and isothiocyanate-modified polysilazane ceramic precursors LANXIDE TECHNOLOGY COMPANY, LP (US) 1991-08-21 EP disclosed
US-5021533-A Intermediate for silicon nitride ceramics HERCULES INCORPORATED (US) 1991-06-04 US disclosed
US-5001090-A Silicon nitride ceramics from isocyanate- and isothiocyanate-modified polysilazanes HERCULES INCORPORATED (US) 1991-03-19 US disclosed
US-4929704-A AMMONIA REACTED WITH HALOSILANES, AMMONOLYSIS, WITH ISOCYANATE, ISOTHIOCYANATE HERCULES INCORPORATED (US) 1990-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060116290-A1 Particulate suspensions PFAS, VCL, JMJD7 CYP3A4 498/4885TRPA1 4071/4885ALDH1A1 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.