SCHEMBL1044718

SCHEMBL1044718

Cc1cc(N=C=O)c(C)cc1N=C=O

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.61
TRPA1 O75762 1/20 0.61
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
MAPK1 P28482 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375132 0.95 CYP3A4 (0.57) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL1191608 0.95 CYP3A4 (0.57) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL1045246 0.92 CYP3A4 (0.59) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL9694213 0.91 CYP3A4 (0.53) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL2170890 0.89 CYP3A4 (0.56) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL11130147 0.87 CYP3A4 (0.50) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL17310624 0.87 CYP3A4 (0.50) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL9693933 0.85 CYP3A4 (0.53) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL15435 0.85 CYP3A4 (0.48) CYP3A4TRPA1TDP1ALDH1A1HPGD
SCHEMBL29381038 0.85 CYP3A4 (0.48) CYP3A4TRPA1TDP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5134189-A Isocyanate, Imino Compound, Polymeric Binder MITSUBISHI PAPER MILLS LIMITED (JP) 1992-07-28 US claimed
US-4849262-A Pigment printing pastes and dyeing liquors containing stable dispersions of finely divided solid polyisocyanates BASF AKTIENGESELLSCHAFT (DE) 1989-07-18 US claimed
US-4321350-A Process for the catalytic setting of polyurethane molding compositions GAMBRO DIALYSATOREN KG (DE) 1982-03-23 US claimed
US-20260146127-A1 COPOLYESTER DERIVED FROM 3-HYDROXYBUTYRIC ACID AND METHOD FOR PRODUCING SAME DIC CORPORATION (JP) 2026-05-28 US disclosed
CN-224242987-U Adhesive tape DIC株式会社 2026-05-15 CN disclosed
US-20260009053-A1 METHOD FOR PRODUCING 1,6-HEXANE DIOL COMPOSITION, 1,6-HEXANE DIOL COMPOSITION, AND POLYMER DIC CORPORATION (JP) 2026-01-08 US disclosed
EP-4640764-A1 POLYAMIDE RESIN COMPOSITION UBE Corporation (JP) 2025-10-29 EP disclosed
US-20250304744-A1 COPOLYESTER RESIN AND METHOD FOR PRODUCING SAME DIC CORPORATION (JP) 2025-10-02 US disclosed
EP-3375799-B1 METHOD FOR PRODUCING SEMI-IPN COMPOSITE AND METHOD FOR PRODUCING MOISTURE-PERMEABLE FILM DAINIPPON INK & CHEMICALS (JP) 2025-09-03 EP disclosed
US-12404377-B2 Fiber bundling agent, fiber material, forming material, and formed product DIC CORPORATION (JP) 2025-09-02 US disclosed
EP-4567056-A1 COPOLYESTER COMPRISING 3-HYDROXYBUTYRIC ACID AND METHOD FOR PRODUCING SAME DIC Corporation (JP) 2025-06-11 EP disclosed
US-4318850-A Carboxamide type azomethine pigment ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-03-09 US disclosed
EP-0010087-B1 PROCESS FOR CATALYTIC HARDENING OF POLYURETHANIC MOULDING MASSES Gambro Dialysatoren K.G. (DE) 1982-02-10 EP disclosed
US-4192684-A Photosensitive compositions containing hydrogenated 1,2-polybutadiene ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-03-11 US disclosed
US-4086211-A Method of producing polyurethane products having an improved flex crack resistance BRIDGESTONE TIRE COMPANY LIMITED (JA) 1978-04-25 US disclosed
US-4085165-A ISOCYANATE PREPOLYMER, VINYL COMPOUND, POLYAMINE OR POLYETHER CURING AGENT BRIDGESTONE TIRE CO., LTD. (JA) 1978-04-18 US disclosed
US-4062825-A SILICA BRIDGESTONE TIRE COMPANY, LTD. (JA) 1977-12-13 US disclosed
US-4032574-A PRODUCTION OF POLYETHERPOLYOLS USEFUL IN PREPARING RIGID POLYURETHANE FOAMS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-06-28 US disclosed
US-4006024-A Photosensitive compositions comprising a polyester-polyether block polymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1977-02-01 US disclosed
US-3960572-A Photosensitive compositions comprising a polyester-polyether block polymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146127-A1 COPOLYESTER DERIVED FROM 3-HYDROXYBUTYRIC ACID AND METHOD FOR PRODUCING SAME HAO2, HAAO, HACD3 CYP3A4 444/4885TRPA1 3480/4885TDP1 2327/4885
US-20260009053-A1 METHOD FOR PRODUCING 1,6-HEXANE DIOL COMPOSITION, 1,6-HEXANE DIOL COMPOSITION, AND POLYMER HAAO, HPD, HDHD5 CYP3A4 586/4885TRPA1 1090/4885TDP1 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.