Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 3/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696167 | 0.77 | ALDH1A1 (0.53) | ALDH1A1CRHBPCRHR2L3MBTL1MEN1 | |
| SCHEMBL120442 | 0.69 | PPARG (0.41) | ALDH1A1CRHBPCRHR2L3MBTL1MEN1 | |
| SCHEMBL4686044 | 0.69 | HTT (0.45) | ALDH1A1SMN1; SMN2GAACYP3A4MAPK1 | |
| SCHEMBL1532324 | 0.69 | ALDH1A1 (0.58) | ALDH1A1CRHBPCRHR2L3MBTL1MEN1 | |
| SCHEMBL27792480 | 0.69 | ALDH1A1 (0.48) | ALDH1A1CRHBPCRHR2L3MBTL1MEN1 | |
| SCHEMBL5285266 | 0.69 | ALDH1A1 (0.45) | ALDH1A1CRHBPCRHR2L3MBTL1MEN1 | |
| SCHEMBL30242985 | 0.69 | MGLL (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL30242982 | 0.69 | MGLL (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL29182467 | 0.68 | ALDH1A1 (0.57) | ALDH1A1CRHBPCRHR2L3MBTL1MEN1 | |
| SCHEMBL20975441 | 0.68 | ALDH1A1 (0.45) | ALDH1A1CRHBPCRHR2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019163-A1 | METHODS AND COMPOSITIONS FOR EDMAN-LIKE REACTIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2011090935-A1 | PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-28 | — | — | WO | disclosed |