SCHEMBL21481741

SCHEMBL21481741

c1ccc(-c2ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5cnccc5n6-c5cc(-c6ccccc6)nc(-c6ccccc6)c5)ccc43)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAOA P21397 4/20 0.39
MAOB P27338 4/20 0.39
ACHE P22303 1/20 0.39
MEN1 O00255 1/20 0.38
HSP90AA1 P07900 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
NPY5R Q15761 1/20 0.38
DHODH Q02127 3/20 0.37
MAPK10 P53779 1/20 0.36
NR3C1 P04150 1/20 0.35
CYP2D6 P10635 1/20 0.34
TSPO P30536 1/20 0.34
HDAC4 P56524 1/20 0.34
PTGER4 P35408 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21481265 0.92 KDM4E (0.46) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL12919330 0.90 CYP19A1 (0.49) CYP19A1KDM4EATML3MBTL1MAOA
SCHEMBL17349308 0.90 KDM4E (0.49) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL15449711 0.90 KDM4E (0.47) KDM4EATML3MBTL1ACHEMEN1
SCHEMBL21481696 0.89 KDM4E (0.43) CYP19A1KDM4EATML3MBTL1MEN1
SCHEMBL21481266 0.89 KDM4E (0.41) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL10309977 0.89 KDM4E (0.50) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL21481767 0.88 ATM (0.42) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL15748496 0.88 L3MBTL1 (0.51) KDM4EATML3MBTL1ACHEMEN1
SCHEMBL10100905 0.88 MAPK10 (0.41) KDM4EATML3MBTL1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
US-20190319197-A1 ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190319197-A1 ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE PIEZO1, OR10J3, OR51E2 CYP19A1 36/4885KDM4E 2904/4885ATM 2334/4885
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF AOX1, ODC1, OTC CYP19A1 44/4885KDM4E 4036/4885ATM 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.