SCHEMBL21484579

SCHEMBL21484579

C/C=C/c1cnccc1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.47
HMGCR P04035 1/20 0.47
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
CYP1A1 P04798 4/20 0.42
CYP1B1 Q16678 4/20 0.42
MAPT P10636 3/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 4/20 0.40
CYP2D6 P10635 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP2E1 P05181 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25403169 0.84 CA12 (0.46) CYP3A4CA12CA1CA2CA9
SCHEMBL9000382 0.83 CA12 (0.42) CYP3A4CA12CA1CA2CA9
SCHEMBL1605930 0.78 ERN1 (0.49) CYP3A4CA12CA1CA2CA9
SCHEMBL30937481 0.78 ERN1 (0.49) CYP3A4CA12CA1CA2CA9
SCHEMBL24248359 0.77 CCNC (0.35) CYP3A4HMGCRCYP1A1CYP1B1
SCHEMBL24601143 0.77 CCNC (0.35) CYP3A4HMGCRCYP1A1CYP1B1
SCHEMBL1605483 0.74 CA12 (0.41) CYP3A4CA12CA1CA2CA9
SCHEMBL2161122 0.74 LMNA (0.41) CYP3A4CA12CA1CA2CA9
SCHEMBL14822558 0.74 SIRT3 (0.38) CYP3A4CYP1A2CYP2D6CYP2E1CYP2A6
SCHEMBL25403165 0.72 CA12 (0.42) CYP3A4CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019196950-A1 COMPOUND TAKING XANTHONE AS CORE AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN OLED 江苏三月光电科技有限公司 2019-10-17 WO disclosed