Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24248359 | 1.00 | CCNC (0.35) | CCNCCDK8APLNRCYP11B1CYP11B2 | |
| SCHEMBL12508937 | 0.87 | IMPDH2 (0.33) | CCNCCDK8 | |
| SCHEMBL18381481 | 0.87 | IMPDH2 (0.36) | CCNCCDK8HTT | |
| SCHEMBL26750323 | 0.84 | CCNC (0.30) | CCNCCDK8 | |
| SCHEMBL14822507 | 0.82 | TRPA1 (0.35) | CCNCCDK8APLNRCYP11B1CYP11B2 | |
| SCHEMBL21881933 | 0.82 | TRPA1 (0.35) | CCNCCDK8APLNRCYP11B1CYP11B2 | |
| SCHEMBL14822558 | 0.82 | SIRT3 (0.38) | APLNRCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL20691108 | 0.81 | CHRNB2 (0.32) | — | |
| SCHEMBL18716205 | 0.80 | GAA (0.43) | CCNCCDK8CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL16130317 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273153-A1 | ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF | Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |