Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605930 | 1.00 | ERN1 (0.49) | ERN1CA12CA1CA2CA9 | |
| SCHEMBL6188476 | 0.91 | CA12 (0.46) | ERN1CA12CA1CA2CA9 | |
| SCHEMBL29935810 | 0.84 | ERN1 (0.49) | ERN1CA12CA1CA2CA9 | |
| SCHEMBL1052852 | 0.84 | ERN1 (0.49) | ERN1CA12CA1CA2CA9 | |
| SCHEMBL25403169 | 0.82 | CA12 (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL16096641 | 0.80 | ALDH1A1 (0.38) | ERN1CA12CA1CA2CA9 | |
| SCHEMBL26119644 | 0.79 | ALDH1A3 (0.39) | ERN1CA12CA1CA2CA9 | |
| SCHEMBL17895679 | 0.79 | CA12 (0.53) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21484579 | 0.78 | CYP3A4 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL26844605 | 0.78 | SLC22A12 (0.51) | ERN1ALDH1A1TSHRTDP1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4629988-A1 | DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER AND INFECTIONS | Centre National de la Recherche Scientifique (FR) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121072-A1 | DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER AND INFECTIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-06-13 | — | — | WO | disclosed |