SCHEMBL21484594

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21484778	0.92	ERBB2 (0.51)	GSTO1LMNAPARP1USP2USP8
	SCHEMBL21484790	0.85	MRE11 (0.51)	GSTO1LMNAPARP1MAPTADORA3
	SCHEMBL21505938	0.85	ERBB2 (0.48)	GSTO1LMNAPARP1HDAC3HDAC4
	SCHEMBL21484887	0.84	LMNA (0.47)	GSTO1LMNAPARP1HDAC1HDAC2
	SCHEMBL21505833	0.83	MRE11 (0.50)	GSTO1LMNAPARP1MAPTADORA3
	SCHEMBL21484775	0.83	MRE11 (0.51)	GSTO1LMNAPARP1MAPTADORA3
	SCHEMBL21484600	0.83	MRE11 (0.58)	GSTO1LMNAPARP1MAPTADORA3
	SCHEMBL21484813	0.83	CSNK2A1 (0.49)	GSTO1LMNAPARP1HDAC3HDAC4
	SCHEMBL21484845	0.83	MEN1 (0.50)	GSTO1LMNAPARP1MAPTADORA3
	SCHEMBL28511010	0.83	MAPT (0.55)	GSTO1LMNAPARP1MAPTADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.