(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL2148473

O=S(=O)(c1ccccc1)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.82
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
ALDH1A1 P00352 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.50
MMP1 P03956 2/20 0.50
MMP2 P08253 2/20 0.50
MMP9 P14780 2/20 0.50
MMP8 P22894 2/20 0.50
MMP13 P45452 2/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
PLA2G7 Q13093 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfonyl)Benzene SCHEMBL28196220 0.95 HTR6 (0.74) HTR6CA1CA2CA12CA9
SCHEMBL3026340 0.95 HTR6 (0.74) HTR6CA1CA2CA12CA9
SCHEMBL197508 0.92 HTR6 (0.78) HTR6CA1CA2CA12CA9
SCHEMBL18194389 0.92 HTR6 (0.68) HTR6CA1CA2CA12CA9
SCHEMBL9001233 0.92 HTR6 (0.68) HTR6CA1CA2CA12CA9
(Phenylsulfonyl)Benzene SCHEMBL4982378 0.91 HTR6 (0.88) HTR6CA1CA2CA12CA9
(Phenylsulfonyl)Benzene SCHEMBL29775288 0.91 HTR6 (1.00) HTR6CA1CA2CA12CA9
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.91 HTR6 (1.00) HTR6CA1CA2CA12CA9
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.91 HTR6 (1.00) HTR6CA1CA2CA12CA9
(Phenylsulfonyl)Benzene SCHEMBL30255 0.91 HTR6 (1.00) HTR6CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681933-B1 POLYMER-METAL JUNCTION SOLVAY SPECIALTY POLYMERS USA (US) 2024-05-15 EP disclosed
US-11359120-B2 Polymer-metal junction SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-14 US disclosed
US-20210122953-A1 POLYMER-METAL JUNCTION SOLVAY SPECIALITY POLYMERS USA, LLC 2021-04-29 US disclosed
EP-3681933-A1 POLYMER-METAL JUNCTION Solvay Specialty Polymers USA, LLC (US) 2020-07-22 EP disclosed
WO-2019053164-A1 POLYMER-METAL JUNCTION SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2019-03-21 WO disclosed
US-20180282483-A1 Polyarylene ether sulfone (PAES) Polymers and Methods for Making the Same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-10-04 US disclosed
US-9868825-B2 Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-01-16 US disclosed
US-9765185-B2 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2017-09-19 US disclosed
EP-3215487-A1 POLYARYLENE ETHER SULFONE (PAES) POLYMERS AND METHODS FOR MAKING THE SAME Solvay Specialty Polymers USA, LLC. (US) 2017-09-13 EP disclosed
US-9611361-B2 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-04-04 US disclosed
US-20140221595-A1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) SOLVAY ADVANCED POLYMERS, LLC (US) 2014-08-07 US disclosed
EP-2342260-B1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) SOLVAY SPECIALTY POLYMERS USA (US) 2014-07-23 EP disclosed
US-8710171-B2 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2014-04-29 US disclosed
EP-2722353-A1 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) Solvay Specialty Polymers USA, LLC. (US) 2014-04-23 EP disclosed
US-20110201775-A1 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-08-18 US disclosed
EP-2342260-A1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) Solvay Advanced Polymers, L.L.C. (US) 2011-07-13 EP disclosed
WO-2010046482-A1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-04-29 WO disclosed
EP-0068695-A1 Blends of poly (parabanic acids) with other polymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-05 EP disclosed
EP-0057104-A2 Polymers containing 1,3-imidazolidine-1,3-diyl rings plasticized with aromatic sulfones or sulfoxides EXXON RESEARCH AND ENGINEERING COMPANY (US) 1982-08-04 EP disclosed
US-4325860-A Polymers characterized by 1,3-imidazolidine-1,3-diyl rings plasticized with aromatic sulfones or aromatic sulfoxides EXXON RESEARCH & ENGINEERING CO. (US) 1982-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201775-A1 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) DHPS, PKM, PCBP1 HTR6 3185/4885CA1 4810/4885CA2 4768/4885
US-20140221595-A1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) DHPS, PKM, PCBP1 HTR6 2956/4885CA1 4797/4885CA2 4749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.