Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14989384 | 0.90 | SMN1; SMN2 (0.65) | HPGDSMN1; SMN2LMNAPKMALDH1A1 | |
| SCHEMBL14997394 | 0.90 | SMN1; SMN2 (0.65) | HPGDSMN1; SMN2LMNAPKMALDH1A1 | |
| SCHEMBL21485090 | 0.82 | SMN1; SMN2 (0.65) | HPGDSMN1; SMN2LMNAPKMALDH1A1 | |
| SCHEMBL6136483 | 0.81 | SMN1; SMN2 (0.60) | HPGDSMN1; SMN2LMNAPKMALDH1A1 | |
| SCHEMBL4418503 | 0.81 | SMN1; SMN2 (0.60) | HPGDSMN1; SMN2LMNAPKMALDH1A1 | |
| SCHEMBL3392569 | 0.81 | GAA (0.62) | HPGDSMN1; SMN2LMNAPKMALDH1A1 | |
| SCHEMBL13851687 | 0.79 | ALDH1A1 (0.62) | HPGDLMNAPKMALDH1A1HDAC3 | |
| SCHEMBL6136527 | 0.78 | SMN1; SMN2 (0.70) | HPGDSMN1; SMN2LMNAPKMALDH1A1 | |
| SCHEMBL14997395 | 0.78 | SMN1; SMN2 (0.70) | HPGDSMN1; SMN2LMNAPKMALDH1A1 | |
| SCHEMBL6136522 | 0.78 | SMN1; SMN2 (0.70) | HPGDSMN1; SMN2LMNAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197015-A1 | COMPOSITION COMPRISING 4-PHENYLBUTYRIC ACID DERIVATIVES & OPIOIDS | TRUOG PETER (CH) | 2019-10-17 | — | — | WO | disclosed |