Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.60 |
| ▸ | PPID | Q08752 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369849 | 0.96 | GAA (0.65) | GAAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3665504 | 0.91 | PPID (0.62) | GAAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3393059 | 0.87 | POLB (0.71) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL13851687 | 0.87 | ALDH1A1 (0.62) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL260297 | 0.83 | ALOX5 (0.76) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL25365126 | 0.83 | HDAC1 (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30385493 | 0.82 | PPID (0.66) | GAAHDAC6HDAC4PPIDPOLB | |
| SCHEMBL8030811 | 0.82 | GAA (0.61) | GAAHDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL27794216 | 0.82 | ALOX5 (0.74) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL21485092 | 0.81 | HPGD (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737819-B1 | AMINO ACID AND PEPTIDE CONJUGATES OF ARYLALKYLIC ACIDS FOR COSMETIC USE | DSM IP ASSETS BV (NL) | 2010-12-22 | — | — | EP | disclosed |
| US-20100099727-A1 | Amino acid and peptide conjugates of arylalkylic acids for cosmetic use | DSM IP ASSETS B.V. (NL) | 2010-04-22 | — | — | US | disclosed |
| US-20080234344-A1 | Amino Acid and Peptide Conjugates of Arylalkylic Acids for Cosmetic Use | DSM IP ASSETS B.V. (NL) | 2008-09-25 | — | — | US | disclosed |
| CN-1934080-A | Amino acid and peptide conjugates of arylalkylic acids for cosmetic use | DSM IP ASSETS BV (NL) | 2007-03-21 | — | — | CN | disclosed |
| EP-1737819-A1 | AMINO ACID AND PEPTIDE CONJUGATES OF ARYLALKYLIC ACIDS FOR COSMETIC USE | DSMIP Assets B.V. (NL) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005092850-A1 | AMINO ACID AND PEPTIDE CONJUGATES OF ARYLALKYLIC ACIDS FOR COSMETIC USE | DSM IP ASSETS B.V. (NL) | 2005-10-06 | — | — | WO | disclosed |
| EP-0207684-B1 | 7-Oxabicycloheptane substituted diamide and its congener prostaglandin analogs | SQUIBB & SONS INC (US) | 1994-11-23 | — | — | EP | disclosed |
| US-4738978-A | ANTICOAGULANT, ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1988-04-19 | — | — | US | disclosed |
| US-4735962-A | ANTICOAGULANTS, BRONCHODILATORS | E. R. SQUIBB & SONS, INC. (US) | 1988-04-05 | — | — | US | disclosed |
| US-4734424-A | ANTICOAGULANTS | E. R. SQUIBB & SONS, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4734426-A | CARDIOVASCULAR AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4734425-A | CARDIOVASCULAR AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4663336-A | ANTICOAGULANTS | E. R. SQUIBB & SONS, INC. (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0207684-A2 | 7-Oxabicycloheptane substituted diamide and its congener prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1987-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234344-A1 | Amino Acid and Peptide Conjugates of Arylalkylic Acids for Cosmetic Use | NGLY1, HRH4, C3AR1 | GAA 2203/4885HDAC3 3471/4885HDAC1 3617/4885 |
| US-20100099727-A1 | Amino acid and peptide conjugates of arylalkylic acids for cosmetic use | NGLY1, HRH4, C3AR1 | GAA 2203/4885HDAC3 3471/4885HDAC1 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.