Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16766999 | 0.85 | LMNA (0.36) | IDO1LMNAMAPTMAPK1NOTUM | |
| SCHEMBL31111685 | 0.80 | IDO1 (0.44) | IDO1LMNAMAPTMAPK1NOTUM | |
| SCHEMBL9438 | 0.78 | CYP1A2 (0.48) | IDO1MAPTMAPK1CYP1A2RAB9A | |
| SCHEMBL31111956 | 0.77 | IDO1 (0.45) | IDO1LMNAMAPTMAPK1NOTUM | |
| SCHEMBL28313237 | 0.77 | — | — | |
| Pyrimidine SCHEMBL28120108 | 0.77 | CYP1A2 (0.40) | IDO1NOTUMCYP1A2RAB9ANISCH | |
| Ammonia Solution, Strong SCHEMBL29843017 | 0.76 | CYP1A2 (0.47) | IDO1MAPTMAPK1CYP1A2RAB9A | |
| SCHEMBL31519384 | 0.76 | CYP1A2 (0.47) | IDO1MAPTMAPK1CYP1A2RAB9A | |
| SCHEMBL30636164 | 0.76 | CYP1A2 (0.47) | IDO1MAPTMAPK1CYP1A2RAB9A | |
| SCHEMBL842040 | 0.76 | CYP1A2 (0.47) | IDO1MAPTMAPK1CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123967-A1 | SARM1 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | SENYA PHARMACEUTICALS, INC. (US) | 2024-06-13 | — | — | WO | claimed |
| WO-2023004280-A1 | SELECTIVE PYRAZOLE LRRK2 INHIBITORS AND METHODS FOR USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-01-26 | — | — | WO | claimed |
| CN-115317489-A | Application of BML-275 in preparation of dormant polyploid giant tumor cell inhibitor | 南通大学附属医院 | 2022-11-11 | — | — | CN | claimed |
| CN-109251214-B | Zinc complex and preparation method and application thereof | 衡水学院 | 2020-12-08 | — | — | CN | claimed |
| CN-108997594-B | Polyacid-based metal organic framework crystal material with polyacid as template | 哈尔滨理工大学 | 2020-11-24 | — | — | CN | claimed |
| CN-105682461-B | Pesticidal combination and relative method | 美国陶氏益农公司 | 2019-06-14 | — | — | CN | claimed |
| CN-109251214-A | A kind of Zn complex and its preparation method and application | 衡水学院 | 2019-01-22 | — | — | CN | claimed |
| CN-108997594-A | A kind of polyacid is the polyacid Base Metal organic frame crystalline material of template | 哈尔滨理工大学 | 2018-12-14 | — | — | CN | claimed |
| EP-4720678-A1 | SURVIVIN AS A BIOMARKER FOR PREDICTING THE RESPONSIVENESS OF CANCER TREATMENT | Boehringer Ingelheim International GmbH (DE) | 2026-04-08 | — | — | EP | disclosed |
| US-12486274-B2 | Substituted pyrazolo-pyrimidines and uses thereof | Verge Analytics, Inc. (US) | 2025-12-02 | — | — | US | disclosed |
| US-20250288589-A1 | PYRIDOPYRIMIDINES AND METHODS OF THEIR USE | Kineta, Inc. | 2025-09-18 | — | — | US | disclosed |
| US-12391690-B2 | Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same | LIGACHEM BIOSCIENCES INC. (KR) | 2025-08-19 | — | — | US | disclosed |
| CN-115209952-B | Substituted pyrazolopyrimidines and use thereof | 维基分析有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-119841847-A | Cyclic 2-amino-3-cyanothiophenes and derivatives thereof for the treatment of cancer | 勃林格殷格翰国际有限公司 | 2025-04-18 | — | — | CN | disclosed |
| WO-2002016380-A1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2002-02-28 | — | — | WO | disclosed |
| EP-1142890-A1 | AMINOPYRAZOLE DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| CN-1049658-C | Pyrazolo[4,3-c]pyridines, a process for their preparation and their use as serotonin reuptake inhibitors | HOECHST MARION ROUSSEL INC (US) | 2000-02-23 | — | — | CN | disclosed |
| CN-1099033-A | Pyrazolo [4,3-c] pyridine, their preparation method and as the purposes of serotonin reuptake inhibitors | HOECHST ROUSSEL PHARMA (US) | 1995-02-22 | — | — | CN | disclosed |
| CN-85105299-A | The preparation method of cephem compounds | — | 1987-01-07 | — | — | CN | disclosed |
| EP-0160969-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12486274-B2 | Substituted pyrazolo-pyrimidines and uses thereof | PIKFYVE, PIP4K2B, PIP4K2C | IDO1 4336/4885LMNA 3896/4885MAPT 770/4885 |
| US-12391690-B2 | Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same | ENPP2, PLA2G10, LPCAT1 | IDO1 390/4885LMNA 4301/4885MAPT 2439/4885 |
| US-20250288589-A1 | PYRIDOPYRIMIDINES AND METHODS OF THEIR USE | PNPO, DPYD, PYGB | IDO1 2417/4885LMNA 1215/4885MAPT 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.