Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15230572 | 0.97 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| Hydrochloric Acid SCHEMBL15230055 | 0.97 | ALDH1A1 (0.54) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| Hypochlorous Acid SCHEMBL21486045 | 0.97 | ALDH1A1 (0.56) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL16782265 | 0.94 | ALDH1A1 (0.59) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| Hydrochloric Acid SCHEMBL15230482 | 0.93 | ALDH1A1 (0.58) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| Hypochlorous Acid SCHEMBL21486014 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| Hypochlorous Acid SCHEMBL21486119 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| Hypochlorous Acid SCHEMBL21486107 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL15229874 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL16782210 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4ERAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2819519-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-10-23 | — | — | EP | claimed |