Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16782210 | 0.97 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL15230411 | 0.96 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| Hypochlorous Acid SCHEMBL21486121 | 0.96 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL15230288 | 0.94 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL15230367 | 0.93 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL15230883 | 0.89 | NPC1 (0.46) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| Hypochlorous Acid SCHEMBL21486116 | 0.86 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| Hypochlorous Acid SCHEMBL21486119 | 0.86 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| Hypochlorous Acid SCHEMBL21486107 | 0.85 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL16782277 | 0.85 | RAB9A (0.54) | ALDH1A1NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2819519-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-10-23 | — | — | EP | claimed |