Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.34 |
| ▸ | HTR3B | O95264 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15231098 | 0.98 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL16782262 | 0.97 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL16782271 | 0.95 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 | |
| Hypochlorous Acid SCHEMBL21486107 | 0.91 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15230328 | 0.88 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL16782251 | 0.87 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 | |
| Hypochlorous Acid SCHEMBL21486014 | 0.86 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 | |
| Hypochlorous Acid SCHEMBL21486143 | 0.85 | NPC1 (0.35) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 | |
| Hypochlorous Acid SCHEMBL21486116 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15230839 | 0.84 | NPC1 (0.42) | ALDH1A1NPC1RAB9AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2819519-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-10-23 | — | — | EP | claimed |